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Privacy Policy · Do Not Sell or Share My Personal Information · California Supply Chain Transparency · Modern Slavery Statement · Terms of Use · Patent Information

AGROTAIN™, the AGROTAIN logo, ANVOL™, the ANVOL logo, CENTURO™, the CENTURO logo, ARMOUR™, the ARMOUR logo, OPTRIENT™, the OPTRIENT logo, N-TEGRATION™, the N-TEGRATION logo, SUPERU™, and the SUPERU logo, TRIBUNE™, the TRIBUNE logo, SYNTHOS™, the SYNTHOS logo, NUTRICARE™, the NUTRICARE logo, WOLF TRAX™, the WOLF TRAX logo, PROTIVATE™, the PROTIVATE logo, 3-TRAX™, DDP™, CROP MIX™, NU-TRAX™ and EVENCOAT™ are trademarks of Koch Agronomic Services, LLC. Koch, the Koch logo and Principle Based Management™ are trademarks of Koch IP Holdings, LLC. © 2025 Koch Agronomic Services, LLC. All Rights Reserved.

1. EPA EEF Challenge Submission data: 30% reduction - corn (Chatterjee et al, 2016); 34% reduction - corn (Chatterjee et al, 2016); 45% reduction - corn (Yang et al, 2016); 35% reduction - corn (Eagle et al, 2017); 48% reduction - irrigated no-till corn (Halvorson et al, 2010); 53% reduction - semi-arid irrigated corn (Dugan et al, 2017); 43.8% reduction - sandy loam soil (Awale and Chatterjee, 2017).

The data and material contained herein are provided for informational purposes only. No warranty, express or implied, is made including, but not limited to, implied warranties of merchantability and fitness for a particular purpose, which are specifically excluded. Results may vary based on a number of factors, including environmental conditions. Before use, consult the product packaging and labeling for information regarding the product's characteristics, uses, safety, efficacy, hazards and health effects.

Not all products may be available in your jurisdiction.

CENTURO is not registered for sale or use in all jurisdictions. In the United States, contact your state pesticide regulatory agency to determine if a product is registered for sale or use in your state. Results may vary based on a number of factors, including environmental conditions. Improvements in nutrient use efficiency, yield and nitrate leaching may not be observed in all cases.

PROTIVATE NU5-LUX is not available for sale, use or distribution in California.

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Latest Resources

fertilizer in a trailerArticleExperts Answer Top Questions on Smarter Phosphorus Managementgrower looking at a handful of treated seed ArticleThe Spring Seed Enhancement Guide: 3 Things to Know Before You Plant wolf trax treated fertilizer in semi trailerArticleThe Evolution of WOLF TRAX™ DDP™ Micronutrients and What It Means for GrowersSPREADERArticle3 Factors to Consider When Selecting an Enhanced Efficiency Fertilizertractor in fieldArticleCombating Nitrogen Loss: A Dual-Action Approach to UAN Stabilization

February 13, 2025

Powered by Pronitridine — Optimize Your Operation with CENTURO™

CENTURO™ nitrogen stabilizer provides growers with a powerful solution to protect their nitrogen investment, minimize losses and optimize yields while simplifying operational processes. With its innovative dual-action nitrification inhibition, proven field performance and user-friendly formulation, CENTURO delivers unmatched value. 

How Nitrification Inhibitors Work

Nitrification is a biological process that converts ammonium (NH4+) into nitrate (NO3-), making nitrogen available for crops. The bacteria Nitrosomonas plays a key role in this process. But this process can get out of control, leading to excessive nitrification that creates nitrogen losses through leaching, impacting crop production and other aspects of agriculture. 

This is where nitrification inhibitors can help. They work by keeping nitrogen in a more stable form readily available for crops to take up over time. Here’s how they work: 

  1. Competitive Inhibition: The inhibitor temporarily blocks the enzyme's active site, slowing down nitrogen conversion.
  2. Non-Competitive Inhibition: The inhibitor changes the enzyme’s shape, further slowing the nitrification process.
  3. Irreversible Inhibition: The inhibitor kills the bacteria responsible for conversion. 

CENTURO: A Different Kind of Nitrification Inhibitor

CENTURO, with its patented active ingredient Pronitridine, has two powerful modes of action designed to slow nitrification – competitive and non-competitive inhibition. This dual action of Pronitridine targets the ammonia monooxygenase, or AMO enzyme, of Nitrosomonas bacteria, blocking its function and altering its shape to disrupt the conversion process. As a result, CENTURO keeps nitrogen in the ammonium form longer, minimizing nitrogen losses and maximizing plant uptake of this critical nutrient. 

competitive and non-competitive inhibition

Proven Field Performance

By managing nitrification and reducing leaching, CENTURO protects a grower’s input investments while enhancing yields, nitrogen use efficiency and overall operational performance. 

University of Nebraska-Lincoln research has found UAN treated with CENTURO consistently lowered soil nitrate levels throughout the entire growing season compared to untreated UAN1. This is one of six university trials demonstrating the effectiveness of CENTURO in reducing nitrate leaching from UAN and NH3 fertilizers. 

When it comes to yield, a multi-state, three-year study showed CENTURO performed as well, or better than Nitrapyrin and improved nutrient use efficiency by up to 25 percent. Fall-applied CENTURO increased corn yield by an average of six bushels per acre over untreated ammonia and spring-applied CENTURO had an average six bushels per acre yield advantage over untreated ammonia2.

Spring and/or in-season side-dress applications with CENTURO offer the added advantage of applying nitrogen closer to when crops need it most. This timing window promotes efficient nutrient uptake and supports optimal corn growth and development.

Corn Yield in Anhydrous Ammonia

Corn side-dress studies further demonstrated CENTURO, at the rate of 1.5 gallons per ton with UAN, had a significant yield advantage over both Instinct II’s (Nitrapyrin) side-dressing application rate and the untreated control3.

Corn Side-Dress Application Rate Efficiency with UAN

Handling Benefits and User Safety

CENTURO was designed with growers’ safety and convenience as top priorities. Its non-hazardous, non-corrosive and low-odor formulation offers a more user-friendly profile than Nitrapyrin. In an 18-month corrosive test CENTURO demonstrated zero corrosive effects on ammonia nurse tank metal, ensuring it is gentle on equipment and reduces downtime associated with equipment damage. 

Benefits and User Safety

References: 

1The underlying data was provided by the University of Nebraska-Lincoln under a Research Trial Financial Support Agreement with Koch Agronomic Services, LLC. Neither these institutions, nor the individual researchers referenced, endorse or recommend any product or service. Improvements in yield and nutrient use efficiency may not be observed in all cases. 
2The underlying data was provided by University of Nebraska, University of Missouri, and the Illinois Fertilizer and Chemical Association under Research Trial Financial Support Agreements with Koch Agronomic Services, LLC. Neither the universities, institutions, nor the individual researchers referenced, endorse or recommend any product or service. Improvements in yield and nutrient use efficiency may not be observed in all cases. 
3The underlying data was provided by Alpha Ag Research, Real Farm Research and Tidewater Agronomics under Research Trial Financial Support Agreements with Koch Agronomic Services, LLC. Neither the universities, institutions, nor the individual researchers referenced, endorse or recommend any product or service. Improvements in yield and nutrient use efficiency may not be observed in all cases. 

Resource Categories
Spring FertilizerFall FertilizerCENTUROArticleNutrient ProtectionAnhydrousUAN

Efficient nutrient management is essential for maximizing crop productivity and profitability. However, nitrogen, a vital nutrient for plant growth, is highly susceptible to losses through leaching, denitrification and volatilization. 

Ready to elevate your nitrogen management strategy? Contact your local KAS sales representative today and discover how CENTURO can help you achieve healthier crops, stronger yields and a more efficient operation.